LCLS offers several instruments that are of interest to the bioscience research community.
The CXI (Coherent X-ray Imaging) instrument takes advantage of extremely bright, ultrashort LCLS pulses of hard X-rays to allow imaging of non-periodic nanoscale objects, including single or small clusters of biomolecules at or near atomic resolution.
Christopher Smith / SLAC National Accelerator Laboratory
The primary capability of the Coherent X-Ray Imaging instrument(CXI) is to make use of the high peak power of the focused X-ray beam using the “diffraction-before-destruction” method. The CXI instrument consists of a highly flexible instrumentation suite to make use of hard X-rays primarily in a vacuum sample environment.
The MFX instrument is primarily focused on macromolecular crystallography at atmospheric pressure. A variety of sample delivery and handling methods are available at this instrument, including a fixed target, rapid scanning goniometer as well as versatile liquid jet systems.
The X-ray pump-probe (XPP) instrument uses ultrashort optical laser pulses to generate transient states of matter which are subsequently probed by hard X-ray pulses from the LCLS. The X-ray pulses help to reveal structural dynamics initiated by the laser excitation at the timescale of atomic motions.