- Minimal concerns with fluid/slurry properties (no clogging, high viscosity, etc.)
- Compatible with some time-resolved experiments (e.g., pump-probe)
- No wasted samples in between pulses if synchronized and sample locations are known
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- Difficult to mount sample onto substrate
- Complicated in-vacuum operation
- Prohibitive in-vacuum machinery
- Need to account for vacuum effects on samples awaiting inspection
- Time-consuming to replace sample-loaded substrates
- Can’t match faster pulse structures
- Need to know sample locations on substrate
- Contribute to background signal from substrate Incompatible with other time-resolved experiments (mixing, complex/multiple pump probes)
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- Large samples (>50 μm)
- Low sample quantity
- Experiments that don’t require vacuum conditions
- Delicate samples that can't handle pressures of liquid injection (high solvent, low lattice contacts, 2-D crystal plates)
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